PRE – CONFERENCE AFTERNOON MASTER CLASSES
September 13th 13:00 – 18:00
Co-Chairs: Anna Marseglia and Hilde van den Brink
Conference room RunAn – Snack and drinks will be delivered at 17.00
Master class 1: VCI - Diagnosis and neuropathological features
Eric Smith, Raj Kalaria
Master class 2: Biomarkers in VCI
Marco Duering – Neuroimaging, Donna Wilcock – Fluid biomarkers from MarkVCID, Carol Cheung – Retinal biomarkers
Master class 3: Future challenges in VCI
Geert Jan Biessels
ECI Mixer
MAIN CONFERENCE
08:30 - 08:40
Opening ceremony – Ingmar Skoog, LOC Chair
THEME 1: WHATS GOING ON? NEW PERSPECTIVES IN VCI – Chairs: Ingmar Skoog & Anna Marseglia
08:40 - 08:50
Invited talk: Sex differences in VCI: from biomarkers to treatment: Lieza Exalto (F), Dept Neurology, UMC Utrecht, the Netherlands
08:50 - 09:00
Invited talk: Resilience pathways in VCI: present challenges and future directions: Prashanti Vemuri (F), Mayo Clinic, USA
09:00 - 09:10
Invited talk: Implementing artificial intelligence methods in VCI: what for? Eric Westman (M), Centre for Alzheimer Research; Department of Neurobiology, Care Sciences, and Society; Karolinska Institutet, Stockholm, Sweden
09:10 - 09:20
Invited talk: Life-time perspective on vascular cognitive ageing / Life-course and Epidemiology: Deborah Gustafson (F), State University of New York Downstate Health Sciences University and Stony Brook (SUNY DHSU, SBU), USA
09:20 - 09:30
Invited talk: New perspectives in neuropathology: Elisabet Englund (F), Division of Pathology, Department of Clinical Sciences, University of Lund, Lund, Sweden
09:30 - 09:40
Invited talk: Brain large artery disease contributions to neurodegeneration: Jose Gutierrez (M), Columbia University, New York, USA
09:40 - 10:10
Discussion
10:10 - 10:25
3 selected abstracts for oral presentation (5 mins each)
10:25 - 10:45
Coffee
THEME 2: BIOMARKERS OF VASCULAR COGNITIVE IMPAIRMENT Chairs: Saima Hilal and Annemieke ter Telgte
10:45 - 10:55
Invited talk: Advanced diffusion MRI markers of cerebral small vessel disease: Anna Dewenter (F), Institute for Stroke and Dementia Research (ISD) Munich, Germany
10:55 - 11:05
Invited talk: Fluid biomarkers in VCI: Henrik Zetterberg (M), University of Gothenburg, Sweden
11:05 - 11:15
Invited talk: Deep learning for detection of Alzheimer’s disease based on retinal images: Carol Cheung (F), Chinese University of Hong Kong
11:15 - 11:25
Invited talk: Cardiac dysfunction, neuroimaging and cognition: Saima Hilal (F), National University of Singapore
11:25 - 12:00
Discussion
12:00 - 12:15
3 selected abstracts for oral presentation (5 mins each)
12:15 - 12:20
12:30 - 14:30
Lunch, poster viewing and discussion at groups of 6 thematic posters, e.g., clinical symptoms, blood pressure, white matter lesions, and brain imaging methods.
13:15 - 14:15
Mixer of global consortia or groups that address the global challenge of Vascular Cognitive Disorders including;
1) The Vascular Theme in UK DRI (Joanna Wardlaw)
2) Vascular PIA-Alzheimer’s Association (Fanny Elahi)
3) STROKOG – the current status (Jessica Lo)
4) An international CADASIL consortium (Raj Kalaria)
5) Meta VCI Map (Geert Biessels)
6) FINESSE – an update (Hugh Markus)
7) International Stroke Genetics Consortium (ISGC) – Genetics of VCID (Stephanie Debette)
8) Reaching international consensus – Delphi and other approaches (P Sachdev)
9) Dementias platform UK (DPUK) (Atticus Hainsworth),
10) Diffusion-weighted imaging positive lesion consortium (DIAGNOSE) (Annemieke ter Telgte)
11) International consortium on cerebral microinfarcts (Saima Hilal)
12) MarkVCID Diverse (Charlie DeCarli)
13) Alzheimer’s Association (Maria Carillo)
14) WW FINGERS (Miia Kivipelto)
The goal is to provide a quick overview of global networks and informal discussion; Chairs: Atticus Hainsworth & Joanna Wardlaw.
14:30 - 15:10
One-minute Poster Blitz:
15:10 - 15:30
Discussion: Chairs: Eric Smith & Audrey Low
15:30 - 16:30
Debate 1: Is SVD a clearly defined clinical and pathological entity Chair: Silke Kern
Group 1 (1) Julie Schneider, (2) Christopher Chen
Group 2 (3) Donna WilcocK, (4) Eric Smith
16:30 - 17:30
Time for VasCog Early Career Investigators meeting with snacks:
– first half: ‘speed dating’ networking
– second half: round table discussion on ECI activities 2024-2025
18:00 - 20:00
08:30 - 08:50
2023 updates – Roxana Carare, SOC Chair
08:30 - 08:40
08:40 - 08:50
THEME 3: INFLAMMATION AND OTHER MECHANISMS OF VCI Chairs: Fanny Elahi & Jae-Sung Lim
08:50 - 09:00
Invited talk: Failure of clearance of fluids from the brain and pathogenesis of CAA: Roxana Carare (F)
09:00 - 09:10
09:10 - 09:20
09:20 - 09:30
09:30 - 09:40
09:40 - 10:10
Discussion:
10:10 - 10:25
Selected abstracts for oral presentation (5 mins each)
10:25 - 10:55
Coffee
THEME 4: PSYCHIATRIC CONDITIONS AND VCI Chairs: Jiyang Jiang & John O’Brien
10:55 - 11:05
Invited talk: Occurrence and prognostic value of neuropsychiatric symptoms in patients with Vascular Cognitive Impairment: Geert Jan Biessels (M), UMC Utrecht, the Netherlands
11:05 - 11:15
11:15 - 11:25
11:25 - 11:35
11:35 - 12:15
Discussion:
12:15 - 12:30
3 selected abstracts for oral presentation (5 mins each)
12:30 - 14:30
14:30 - 15:10
One-minute Poster Blitz:
15:10 - 15:30
Discussion: Chairs: Fanny Elahi & Satoshi Saito
15:30 - 16:30
Debate 2: ATN classifications – updating e.g., VATN Chair: Raj Kalaria
Group 1 Kaj Blennow
Group 2 Fanny Elahi
16:30 - 17:30
Business meetings: Executive Committee (Chaired by Gustafson)
18:00 - 20:00
20:00
Vas-Cog Party: Kajskjulen 8, Packhusplatsen 11, 411 13 Göteborg, Sverige
08:40 - 08:50
THEME 5: NEW DIAGNOSES AND CLASSIFICATIONS Chairs: Hugh Markus & Hilde van den Brink
08:50 - 09:00
Invited talk: The Boston 2.0 criteria: TBA
09:00 - 09:10
Invited talk: STRIVE-2 criteria: Joanna Wardlaw (F), Edinburgh, UK
09:10 - 09:20
09:20 - 09:30
Invited talk: ARIA-E and ARIA-H: Sandra Black (F), University of Toronto, Canada
09:30 - 10:15
Discussion:
10:15 - 10:30
3 selected abstracts for oral presentation (5 mins each)
10:30 - 11:00
Coffee
THEME 6: WHATS NEW IN TREATMENT AND PREVENTION OF VCI? Chairs: Masafumi Ihara & Satoshi Hosoki
11:00 - 11:10
Invited talk: WW FINGER: Miia Kivipelto (F), Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden
11:10 - 11:20
Invited talk: Optimising trial design FINESSE: Hugh Markus (M), University of Cambridge, UK
11:20 - 12:30
11:30 - 11:40
Invited talk: AMCAD study: a multicenter randomized phase II study for CADASIL: Masafumi Ihara (M), National Cerebral and Cardiovascular Center, Osaka, Japan
11:40 - 12:10
Discussion:
12:10 - 12:25
3 selected abstracts for oral presentation (5 mins each)
12:25 - 12:35
12:35 - 12:40
12:40 - 13:00
13:00 - 14:00
Business meetings: General assembly